The 2006 paper suggested an amyloid beta (Aβ) protein called Aβ*56 could cause Alzheimer’s.
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For years researchers had tried to improve Alzheimer’s outcomes by stripping amyloid proteins from the brain, but the experimental drugs all failed. Aβ*56 seemed to offer a more specific and promising therapeutic target, and many embraced the finding. Funding for related work rose sharply.
